Salvia Divinorum - Extraction, Purification and Infusion

Wouldn't it be great if  instead of relying in leaf matter with unknown potency you could make standardized dosages of salvinorin-A?

This TEK will teach you how to make a decent extract of salvinorin-A and how to infuse it in rolling papers

Extraction:

1. Start with 250g or more of crushed leaves. The more leaves used, the easier it is to limit loss.

2. In batches (I used batches of 30g each), cover leaves with 0°F acetone and agitate/stir for 1 minute. Pour off acetone through a very fine strainer. Repeat 2 more times. (An extraction requires 3 minutes!)

3. Allow collected acetone to settle for 24 hours in a dark area. There will be sediment at the bottom of your container. Siphon off as much acetone as possible, being careful not to disturb sediment. Discard sediment.

4. Allow acetone to evaporate in a dark, well-ventilated area. You will be left with a bright green powder – about 1g per 100g of leaf. This powder is about 2 parts chlorophyll to 1 part salvinorin A.

Purification:

5. Chlorophyll is somewhat soluble in naphtha, salvinorin A is insoluble in naphtha. Collect powder, and add about 50mL naphtha per gram, mix well. Allow to settle for several hours or overnight. Much of the chlorophyll will dissolve in the naphtha.

6. Siphon off as much naphtha as possible, being careful not to disturb sediment – the sediment is salvinorin A. Discard used naphtha.

7. Repeat steps 5, 6 two or three times – until no more chlorophyll will dissolve.

8. Chlorophyll is very soluble in isopropyl alcohol, salvinorin A is slightly soluble (0.7mg/mL). This step will remove all remaining chlorophyll, but will reduce yield especially if you use IPA liberally. Add about 50mL 99% IPA to sediment from step 6. (This will result in a loss of 35mg salvinorin A, but will remove most of the chlorophyll.) Stir, then allow to settle.

9. Siphon off IPA and repeat step 8 two more times. (Save the IPA – you might be able to get some salvinorin A out of it if you evap. it all and then repeat step 8 with the results.)

10. Add about 100mL or more acetone to the sediment. Stir. The salvinorin A will dissolve completely, some insoluble material will remain. Allow sediment to settle.

11. Siphon off acetone and put it in an evaporation dish. Discard sediment.

Infusion:

I don't like the TEK i saw regarding this, there's just no way to get the same dosage across every piece of paper, using the same method as laying blotter seems a better and safer procedure.

12 - Measure the absorbency of a rolling paper by first saturating it with acetone, meaning to the point where it is completely wet but is not dripping or sweating anything whatsoever. This is done by first weighing exactly how many milligrams the dry paper weighs and subtracting that number from the wet/saturated weight. This gives you the weight of the maximum amount of solvent your paper can take.

13 - How to proceed depends on whether you plan on measuring that calculated amount of solvent using equipment that can measure weight or volume very accurately. If you go by volume you need the density of the solvent of choice. Let's call this amount of acetone X

14 - In how many pieces do you want to cut your rolling paper? I'd say 30 is a good number, not to big, not to small, perfectly smokable

15 - Dissolve the pure salvinorin-A in acetone, make sure to get a density of 30 mg per X ml

16 - Submerge the desired number of papers in the salvinorin solution (X ml will be absorbed per piece of paper)

17-  In a flat evaporation dish allow acetone to evaporate from the papers

18 - Cut every rolling paper in 30 pieces, they should be all the same size!

19 - Each piece of paper now contains 1mg salvinorin-A, if you made it this far you now have your standardized dosages, just put a piece in a pipe and light up!

A better approach would be to cut the papers first and use a dropper to get the desired amount of salvinorin-A in each piece, for example making a 1mg/ml solution of Salvinorin-A and dropping 1ml individually in each piece, with the previous method you get slightly stronger pieces in the corners of the papers

And before you ask, no, this can't be dosed as blotter, bucal salvinorin-A absorption is just awful

Sources:

Salvia Chilled acetone extraction by Sphere - Pdf File
Infusing Rolling Papers with salvinorin-A - Pdf File
DMT-NEXUS