Dendrobium Nobile - Side Effects

Sometime ago i made a post about Dendrobium Nobile, the source of that info also has a trip report about bad side effects, it would be irresponsible not to share that info, this is a good example of why you shouldn't do drugs when you are already sick, specially unknown ones. I Think this report does a good job on harm reduction advice, read it carefully

Here is an hypothesis of what might have happened:

"The symptoms of a cold are caused by the immunitary system fighting the infection. Now some of the compounds in the orchid have immunomodulatory effects. Maybe I ingested a lot of these compounds along with the psychoactive ones and they caused a strong reaction from the immune system fighting the infection and I am currently experiencing a hyperactive immune system."

Now the trip report itself:

"I have not slept this night. I was distracted the whole night by almost any inner and outer stimulus. I heard the wind in the trees and other nightly noises outside, saw light from technical equipment in the room, and from streetlights and passing cars and was constantly engaged in my stream of consciousness and could not find a comfortable position. I was just not able to shut of my daily functioning and go over to sleep. Also I felt a little sick. Cold feet, a little headache and generally a feeling like a starting cold. But all in all I am not feeling to bad about it. I had some great ideas and insights into things that were on my mind lately. Maybe a bit of a "forced meditation" could be a valid description. Overall I am feeling a little exhausted now, but should be capable of managing my day.

On the other hand, I have to say that I was too careless and I also underestimated the orchid.
Here are the things that could have contributed to this nights' experience.
I had a little Cannabis after I was back to baseline and I also drank some mate
Both substances did by themselves never effect my ability to go to sleep before. Therefore there could be some interaction there.
Also I did a drastical increase in the dose. From "half a flower" to a pretty big part of the stem (1,7g fresh/ ~180mg dry). I never tested something before that had so little information about effects, side effects, neuronal background, dose... damn, even the active compound is unknown! With everything else, I was always more careful than necessary, always testing recommended small doses and always on the safe side. Now I wanted the test the full effects (I was excited testing something almost unknown) and also did not want to take any more material from my plant. Therefore I took a big leap from a known active dose, to maybe two or three times that much. I just did not expect this at all! Stupid! Lesson learned 

Start with a dose you would not expect effects from, then gradually increase until full effects are met or side effects are noticeable.

I was also feeling not completely well the last few days, so illness symptoms could just be coincidental or in some kind triggered by the consumption.

Also I have a pretty unhealthy sleep rhythm, staying up late, sleeping only very short and catching up on sleep later. But there are usually no problems going to sleep, when I'm in bed. So again, the consumption might just have triggered something.

All in all there were too many influences to decide where these effects came from.

To all of you who want to experiment: Be careful! Try small doses. Only increase gradually. Don't mix with anything."

Next day he added the following:

"Today in the afternoon I became sick, with headaches, cold arms and legs and nausea and maybe a little fever. I just pucked most of what little I ate today and feeling a bit better since. (enough to work with the laptop)From the symptoms I am pretty sure that this is the cold I had small symptoms from maybe the last two weeks and perhaps even longer. "