DPCPX :: Caffeine Analogue :: Psychedelic Potentiator

I love caffeine, so i decided to take a look at some analogues out there, therefore I present you my favorite!

The Analogue

Meet Dipropylcyclopentylxanthine, or DPCPX, this caffeine analogue acts as a phosphodiesterase inhibitor, and is almost as potent as the nootropic rolipram at inhibiting PDE4, Like most PDE4-inhibitors, it is an anti-inflammatory drug.

PDE4 Inhibition

PDE4 inhibitors have proven potential as anti-inflammatory drugs, especially in inflammatory pulmonary diseases such as asthma, COPD, and rhinitis. They suppress the release of cytokines and other inflammatory signals, and inhibit the production of reactive oxygen species. PDE4 inhibitors may have antidepressive effects and have also recently been proposed for use as antipsychotics, not sure if all this applies to DPCPX but I'm guessing it does!

Uses of DPCPX

DPCPX has been used to study the function of the adenosine A1 receptor in animals, which has been found to be involved in several important functions such as regulation of breathing and activity in various regions of the brain, as well as having interactions with a range of anticonvulsant drugs.

Phenethylamine Potentiation

DPCPX has also been shown to produce behavioural effects such as increasing the hallucinogen-appropriate responding produced by the 5-HT2A agonist DOI, and the dopamine release induced by MDMA,

Check this study regarding the potentiation of DOI trips

And this one regarding potentiation of MDMA

Overview 

What this means is that DPCPX probably potentiates all Phenethylamines!

So a particularly nootropic caffeine derivative that enhaches the effects of a trip? Interesting...

Now, i don't understand that much about all this, but from the little i gathered i speculate the following benefits:

• Improved long term memory
• Increased Wakefulness (like in CPX)
• Increased Neuroprotection
• Enhancement of Phenethylamine Psychedelic Trips
• Increase of the dopamine release induced by MDMA and possibly other dopaminergic drugs

I am curious to try this compound, however there have been no toxicological reports that i am aware off, so i don't recommend you start ingesting this without some further studies! I will keep vigilante regarding this subject, if it proves to be safe i shall make some trip reports!

Warning: Even tough many of my posts are speculative, this one is particularly under-researched (by me), made on a hurry and prone to errors, as always caution is advised

For further reading check the DMT-Nexus Thread where i got most of this info