About Synth Noids - Dangers and Overdose Report

Been reading a bit about synth noids and remembering about the time blends were available everywhere and people were ODing often and going to the ER.

Since then there have been a few studies and we now know a little more about their effects, the bad ones include but are not limited to:

• Acute Kidney Injury
• Death
• Agitation,
• Seizures,
• Hypertension,
• Emesis (vomiting)
• Hypokalemia (low potassium levels).
• Breathing difficulties, 
• Tight Chest, 
• Racing heart, 
• Palpitations, 
• Shakes and Sweats which can lead to severe panic. 
• With higher doses balance and psychomotor skills can be severely impaired
• Loss of feeling and numbness in limbs,
• Tolerance to synthetic cannabinoids develops quickly, with increasing dosage and compulsive use commonly reported

Hopefully after reading this small post you wont want to try synth noids, and if you do, you wont buy pre-made blends.

There's an "overdose report" in the end of this post so you can understand what it feels like to be irresponsible

2M2B - Gets you drunk but it ain't ethanol

2-Methyl-2-Butanol

2M2B is more potent than ethanol so dilution is advised, it's supposed to taste mint-ish so it could make some fine cocktails.

Tertiary alcohols like 2M2B cannot be oxidised to aldehyde or carboxylic acid metabolites, which are often toxic; this makes them safer drugs than primary alcohols

This means hangover should be pretty much non-existent if you stay hydrated since dehydration and acetaldehyde are the primary hang-over causes.

Trip reports say there's still an hangover tough, but much weaker than a normal ethanol hangover

BK-2CI

This is another novel chem that appeared on the market (once again from Royal Alchemist), there are very little reports on this, i may be doing some testing with the stuff.

IUPAC name - 2-amino-1-(4-iodo-2,5-dimethoxyphenyl)ethan-1-one.

The dosage seems to be equivalent to BK-2CB, the only trip report i could find seems to indicate low psychedelic value and no side-effects. So far it seems a proper stimulant rather than a psychedelic which is to be expected from the Beta-Ketone moiety, but further tests are needed since we only have a single (disappointing) report so far

5-MeO-MALT

Royal Alchemist are now stocking 5-MeO-MALT, since around the forums there seems to be some interest on this i compiled some info

N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-N-methylprop-2-en-1-amine

5-MeO-MALT is a very new tryptamine that has very little information about it. If you plan on using it please start low and work your way up.

Tryptamine Review #5 - DET

DET - Diethyltryptamine

Dosage:

Smoked/Vaporized DET Dosages Threshold unknown Light 20 - 30 mg Common 40 - 60 mg Strong 70 + mg

Onset : 2 - 5 minutes

Tryptamine Review #4 - 4-aco-met

4-Acetoxy-MET

Dosage:

Threshold : 5 - 10mg
Light : 10 - 20mg
Common : 20 - 30mg
Strong : 30 - 40mg
Heavy : 40mg+

Sweet spot - 40-60mg snorted

Tryptamine Review #4 - 4-Aco-MET

4-Aco-MET

Depth -3/10. 

Very little depth here, to be honest. None of the spiritual/philosophical insights that can be gained from shrooms. There is a definite change in consciousness and a bit of psychedelic confusion, but it’s mostly just a visual trip.

Tryptamine Review #3 - DPT

Lysergury @ chemsrus had a great idea for a thread trying to explain the subjective difference between different tryptamines, i'm hijacking his idea and posting the relevant info here.

I'm really interested in trying this tryptamine, seems exactly my kind of drug!

DPT

Dosage:

Personally I find an insufflated dose of 100 mg to be ideal. The effects last about 3 hours. Vaping works well too, although I find this method to be borderline TOO intense (ie difficult to understand/assimilate the experience). If that's what you're looking for though, light that shit up.

Vaping provides a much shorter, more intense experience. The effects hit you immediately and last about an hour. I'd say 50 mg vaped would be enough to completely blast off. Although I would advise starting small and working your way up, as dosages seem to vary with DPT more so than other substances.

I would advise against taking it orally as this ROA weakens the effects considerably (ie you have to take more). It can also be injected IM but I haven't personally tried that method.

Tryptamine Review #2 - 4-HO-MiPT

4-HO-MiPT

Come up - approx 1 hr, maybe alerts as soon as 10 minutes

Peak - around 2 hours for me consistently. Others have claimed 4-6

Comedown - no noticeable comedown. It's like blinking and then it's gone. Nice afterglow though which can easily last into the next day or so.

Depth - 2/10

I did not have any deep thoughts or realizations from 4-HO-Mipt. I have heard others say this is a mentally trying synth but that was not my experience in reasonable doses. At a ridiculously high dose, I did experience a full blown panic attack so take that for what it's worth. If you want to read about it click Here

Tryptamine Review #1 - 5-Meo-DALT

Lysergury @ chemsrus had a great idea for a thread trying to explain the subjective difference between different tryptamines, i'm hijacking his idea and posting the relevant info here.

5-Meo-DALT

Dosage: 

10-30mg Oral. 

5-11mg iv. 

Insulfated or vaporized/pyrolized is unknown to me.

Depth: 1/10 

via the ROAs I've researched, in the dosage range I've researched, 5-meo-dalt is not a deep material. This is not to say it is a bad material- the complete and total lack of any mindfuck or time-dilation whatsoever is actually a wonderful quality for more recreational purposes, if not for spiritual/introspective ones. It is very pro-social, mildly euphoric (iv doses are extremely euphoric), and mildly entactogenic/empathogenic without any kind of overpowering mystical push.

N-acetylcysteine - Nootropic, medicine, psychiatric tool

For a while I've been wanting to write about N-acetylcysteine, but i found the perfect post about it over at DMT-Nexus, so i will literally just copy paste, forgive my laziness but i couldn't improve this post at all!

Adventures in Neuroscience - Episode 1 - NAC

By: The Cosmic Lion

If you don't care about the science or my explanation, skip straight to the Conclusions section at the end for the concise summary and dosage recommendation!

NAC, or N-acetylcysteine, can be found over the coutner at most GNC's and many health food stores. GNC sells the 600mg pills, fairly weak, it is ideal to seek the 1,000mg pills due to the high recommended dosages.

NAC is all at once a nooptropic (smart drug), a physical medicine, and a serious psychiatric tool

NAC is an acetylized version of the natural amino-acid cysteine that is a precursor to Glutamate, which effects the Glutamate system, which is responsible for learning, memory, motivation and cognition. It has a TON of medical application already. Additionally, recent studies show psychiatric effects on the glutmate, dopamine and NMDA brain systems.

Bear with me here, this post is long but filled with goodies. I present you here with MY summary, Wiki + WedMD info, then at the end the NEW info regarding its new use in psychiatry (Including a CUSTOM dose recommendation!). I will also explain the relevance of each quote after its posted. Stay tuned.

LSH - Lysergic Acid Hydroxyethylamide

LSA is not a very interesting compound on itself, but it easily forms adducts, most aldehydes bind with it making a new compound, much more psychedelic! 

The reaction between LSA and acetaldehyde is tought to produce LSH (Lysergic Acid Hydroxyethylamide)

DPCPX :: Caffeine Analogue :: Psychedelic Potentiator

I love caffeine, so i decided to take a look at some analogues out there, therefore I present you my favorite!

The Analogue

Meet Dipropylcyclopentylxanthine, or DPCPX, this caffeine analogue acts as a phosphodiesterase inhibitor, and is almost as potent as the nootropic rolipram at inhibiting PDE4, Like most PDE4-inhibitors, it is an anti-inflammatory drug.

25c-NBOH - effects overview

25-C-NBOH (2C-C-NBOH, NBOH-2CC) is a derivative of the phenethylamine derived hallucinogen 2C-C. It has similar serotonin receptor affinity to the better-known compound 25C-NBOMe

Just leaving some quick info about 25c-NBOH effects, expect a more detailed post later

Findings from reading Trip Reports:

• very visual, little mind fuck, visuals are a bit boring (strong but boring)
• 500ug is a low dose, 1000ug a high dose and 750ug probably a medium dose
• it hits quickly (30min or so) and lasts 4-5h (buccal dosing)
• emotionally neutral (aka doesn't cause anxiety nor euphoria)
• possible but rare bodyload (nausea, vasoconstriction, excessive stimulation)
• felt fine next day
• overal if you consider the price it's not that bad, but there are better substances around both for people looking for something with low mind fuck and good visuals (for example 4-ho-met) and for people that want both the psy headspace and visuals

Sea DMT - Psychedelic Sponges

I found an interesting article on sea sponges containing high concentrations of 5-bromo-DMT as well as some human bioassays ("trip reports") from those who have tried synethtic 5-bromo-DMT. Their reports are incredibly interesting. I wonder if you can take it orally, or if not, orally with an MAOI?

Some speculate this is perhaps the reason behind the hallucinogenic fish poisoning reports from the Sarpa sarpa species back in 2006.

Prepare yourself for a very interesting read!

LSA

Today im going to make a post about LSA. This will function as a starting point to some other compounds that i wish to talk about (LSH, LSC....)

LSA (d-lysergic acid amide, ergine) is a psychedelic ergoline alkaloid closely related to LSD. It can also be used as precursor to LSD synthesis

An LSA experience is characterized by effects similar to those of LSD, for example auditory and visual hallucinations, spatial and temporal distortion, introspection, etc. It is a powerful psychedelic (roughly one-tenth the potency of LSD, with a threshold dose of ~500 micrograms),

BK-2CB

This sounds like an interesting material, which has supposedly become available. I can't find much information about it yet. There are some trip reports out there. It makes it seem like bk-2-cb is a proper psychedelic rather than a stimulant.

IUPAC: 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)ethan-1-one

Routes: Oral, Insufflated, Rectal

Formula: C10H12BrNO3 

Molecular mass: 274.111

βk-2C-B is a psychedelic drug which is structurally related to 2C-B and methylone. It has similar effects to these drugs in humans and has been used as a recreational drug.

How Does Caffeine Work?

How many of you have wondered how does caffeine work? we have the short answer!

First, a little biology. As your neurons fire throughout the day, a neurochemical called adenosine builds up in your body. The nervous system uses special receptors to monitor your body’s adenosine levels. As the day wears on, more and more adenosine passes through those receptors—and it makes you sleepy. It’s one of the reasons you get tired at night.